Our research goal is to understand the biological phenomena at the molecular level by using simulations and theoretical tools based on chemistry and physics. Biological systems are maintained through a numerous interactions between biological constituents whose dynamics are characterized by the broad spectrum of time and length scales, thereby our primary interest ranges from the dynamics associated with the self-assembly and mechanical response of biopolymers (DNA, RNA, and proteins) at the single molecule level to the interactions among those molecules ultimately responsible for the biological functions. Together with the current approach employing theoretical/computational molecular biophysics and statistical mechanics, further studies toward understanding the biological phenomena at the system level will be a long term research plan of our group.